Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.341
Abstract: Tenapanor (RDX5791/AZD1722) is a minimally systemic small‐molecule inhibitor of the sodium/hydrogen exchanger NHE3. Tenapanor acts in the gut to reduce absorption of sodium and phosphate. This phase 1 open‐label, 3‐way crossover study (NCT02226783) evaluated the… read more here.
Keywords: effect food; mmol day; food; sodium ... See more keywords
Protective Effect of Food Against Inactivation of Human Coronavirus OC43 by Gastrointestinal Fluids
Sign Up to like & getrecommendations! Published in 2022 at "Food and Environmental Virology"
DOI: 10.1007/s12560-022-09520-5
Abstract: The involvement of the gastrointestinal (GI) tract in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has been reported in multiple studies. Since it has been demonstrated that human intestinal epithelial cells support productive viral replication… read more here.
Keywords: effect food; inactivation; food; gastrointestinal fluids ... See more keywords
The serving temperature effect: Food temperature, expected satiety, and complementary food purchases
Sign Up to like & getrecommendations! Published in 2021 at "Appetite"
DOI: 10.1016/j.appet.2020.105069
Abstract: We show that the temperature at which foods and beverages are served impacts consumers' complementary purchases, defined as additional foods and beverages purchased for a consumption episode. Across a series of studies, including field studies… read more here.
Keywords: effect food; temperature; serving temperature; complementary food ... See more keywords
The effect of food, vitamin or mineral supplements on chronic constipation in adults: a systematic review and meta-analysis of randomised controlled trials
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665123000307
Abstract: BACKGROUND Over-the-counter supplements are commonly used to manage chronic constipation; however, their efficacy remains unclear. We aimed to investigate the effect of food, vitamin or mineral supplements on stool output, gut transit time, symptoms, and… read more here.
Keywords: chronic constipation; mineral supplements; vitamin mineral; constipation ... See more keywords
Effect of food on capsule and granule formulations of selumetinib.
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DOI: 10.1111/cts.13209
Abstract: Selumetinib is an oral, potent, and highly selective allosteric MEK1/2 inhibitor approved for the treatment of pediatric patients (aged ≤2 years) with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas. A granule formulation of selumetinib… read more here.
Keywords: effect food; granule formulations; capsule granule; selumetinib ... See more keywords
In Vitro Release Kinetics of Microencapsulated Materials and the Effect of the Food Matrix.
Sign Up to like & getrecommendations! Published in 2017 at "Annual review of food science and technology"
DOI: 10.1146/annurev-food-030216-025720
Abstract: Many biomaterials are encapsulated to preserve their health-promoting properties and promote targeted delivery. Numerous papers have been published about extraction and purification methods, encapsulation techniques, and release properties of encapsulated biomaterials. Despite the abundant information,… read more here.
Keywords: effect food; food; food matrix; release ... See more keywords
The effect of food anticipation on cognitive function: An eye tracking study
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DOI: 10.1371/journal.pone.0223506
Abstract: By randomizing the order in which participants perform a cognitive test and a food choice task in a controlled experiment, we investigate whether cognitive capacity can be enhanced by the simple act of anticipating food… read more here.
Keywords: effect food; effect; food; food anticipation ... See more keywords
The Effect Of Food On The Pharmacokinetic Properties And Bioequivalence Of Two Formulations Of Levocetirizine Dihydrochloride In Healthy Chinese Volunteers [Erratum]
Sign Up to like & getrecommendations! Published in 2019 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s236661
Abstract: [This corrects the article DOI: 10.2147/DDDT.S215316.]. read more here.
Keywords: pharmacokinetic properties; effect food; bioequivalence two; food pharmacokinetic ... See more keywords
Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2023 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s388846
Abstract: Objective This study aimed to investigate the effect of food on the pharmacokinetics and safety profiles of SCC244, a novel oral c-Met inhibitor in healthy Chinese male subjects. Methods It was a randomized, open-label, and… read more here.
Keywords: state; safety; pharmacokinetics safety; effect food ... See more keywords
Effect of Food Order on Ghrelin Suppression
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes Care"
DOI: 10.2337/dc17-2244
Abstract: Data suggest that the temporal sequence of carbohydrate ingestion during a meal has a significant impact on postprandial glucose (1–3), insulin, and glucagon-like peptide 1 (GLP-1) excursions (4) in type 2 diabetes, while the effects… read more here.
Keywords: suppression; effect food; food order; ghrelin suppression ... See more keywords
The effect of food on the pharmacokinetics of WXFL10203614, a potential selective JAK1 inhibitor, in healthy Chinese subjects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1066895
Abstract: Objective: This study was performed to investigate the effect of food on the pharmacokinetics (PK) of WXFL10203614 in healthy Chinese subjects. Methods: This was a randomized, open-label, single-dose, two-treatment (fed vs fasted), two-period, two-sequence, crossover… read more here.
Keywords: chinese subjects; food; effect food; food pharmacokinetics ... See more keywords