Antiamyloid β toxicity effect of genistein via activation of DAF‐16 and HSP‐16.2 signal pathways in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23055
Abstract: β‐Amyloid toxicity (Aβ) is an important pathological factor of Alzheimer's disease (AD). Studies have shown that genistein can reduce the toxicity of Aβ to a certain extent; however, the specific mechanism is still uncertain. In… read more here.
Keywords: effect genistein; hsp; toxicity; caenorhabditis elegans ... See more keywords
Protective effect of genistein on the ischemic acute kidney injury in the rat.
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DOI: 10.1016/j.gene.2020.144789
Abstract: BACKGROUND This study determined the possible anti-inflammatory and antioxidant renal protective effect of genistein, a soy isoflavone, against kidney damage and functional disorders following renal ischemia/reperfusion (I/R) in male rats. MATERIALS AND METHODS The animals… read more here.
Keywords: genistein; protective effect; effect genistein; sham ... See more keywords
The effect of genistein on TGF-β signal, dysregulation of apoptosis, cyclooxygenase-2 pathway, and NF-kB pathway in mice peritoneum of endometriosis model
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DOI: 10.1016/j.mefs.2017.05.002
Abstract: Abstract This research aimed to investigate the effect of genistein on TGF-β, dysregulation of apoptosis, NF-κB pathway, COX-2 pathway in mice of endometriosis model. Twenty-eight female mice ( Mus musculus ) were divided into seven… read more here.
Keywords: endometriosis; dysregulation apoptosis; endometriosis model; genistein tgf ... See more keywords
Antimutagenic effect of genistein
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DOI: 10.17221/3306-cjfs
Abstract: A great variety of health benefits including the protection against breast and prostate cancers has been attributed to the soya consumption, because of the presence of soy beans isoflavones, genistein, and others. We investigated the… read more here.
Keywords: genistein; effect; antimutagenic effect; test ... See more keywords
The Effect of Genistein Supplementation on Cholesterol Oxidation Products and Fatty Acid Profiles in Serums of Rats with Breast Cancer
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DOI: 10.3390/foods11040605
Abstract: The aim of this study was to assess the effect of genistein on the level of cholesterol, oxysterols, and composition of fatty acids, as well as enzymatic activity of desaturases, in rats with breast cancer.… read more here.
Keywords: effect genistein; supplementation; rats breast; breast cancer ... See more keywords