The Effect of Hepatic Impairment on the Pharmacokinetics of Intravenously Administered Felcisetrag (TAK‐954)
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DOI: 10.1002/jcph.2044
Abstract: Felcisetrag (formerly known as TAK‐954) is a selective serotonin receptor agonist under investigation for use in patients with postoperative gastrointestinal dysfunction. The safety, tolerability, and pharmacokinetics (PK) of intravenous (i.v.) felcisetrag have been studied, but… read more here.
Keywords: effect hepatic; hepatic impairment; time; felcisetrag ... See more keywords
Cell non-autonomous effect of hepatic growth differentiation factor 15 on the thyroid gland
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DOI: 10.3389/fendo.2022.966644
Abstract: The thyroid gland plays an essential role in the regulation of body energy expenditure to maintain metabolic homeostasis. However, to date, there are no studies investigating the morphological and functional changes of the thyroid gland… read more here.
Keywords: effect hepatic; gdf15; differentiation factor; growth differentiation ... See more keywords