Computational Prediction of a New ADMET Endpoint for Small Molecules: Anticommensal Effect on Human Gut Microbiota
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00600
Abstract: The human gut microbiota (HGM), which are evolutionarily commensal in the human gastrointestinal system, are crucial to our health. However, HGM can be broadly shaped by multifaceted factors such as intake of drugs. About one-quarter… read more here.
Keywords: anticommensal effect; effect human; human gut; effect ... See more keywords
Therapeutic effect of human adipose-derived stem cells and their secretome in experimental diabetic pain
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09487-5
Abstract: Painful neuropathy is one of the complications of diabetes mellitus that adversely affects patients’quality of life. Pharmacological treatments are not fully satisfactory, and novel approaches needed. In a preclinical mouse model of diabetes the effect… read more here.
Keywords: effect human; hasc hasc; therapeutic effect; effect ... See more keywords
Effect of human very low-density lipoproteins on cardiotrophin-like cytokine factor 1 (CLCF1) activity
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22400-y
Abstract: The cytokines CLCF1 and CNTF are ligands for the CNTF receptor and the apolipoprotein E (ApoE) receptor sortilin. Both share structural similarities with the N-terminal domain of ApoE, known to bind CNTF. We therefore evaluated… read more here.
Keywords: effect human; cytokine; apoe; clcf1 activity ... See more keywords
Quantifying the effect of human practices on S. cerevisiae vineyard metapopulation diversity
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73279-7
Abstract: Saccharomyces cerevisiae is the main actor of wine fermentation but at present, still little is known about the factors impacting its distribution in the vineyards. In this study, 23 vineyards and 7 cellars were sampled… read more here.
Keywords: effect human; grape; farming system; quantifying effect ... See more keywords
Effect of human leukocyte antigen mismatching on the outcomes of pediatric kidney transplantation: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfx259
Abstract: Background Kidney transplantation is regarded as the optimal treatment for pediatric patients with end-stage renal disease. Here, we address a controversial topic in pediatric kidney transplantation by performing a quantitative evaluation of the effect of… read more here.
Keywords: pediatric kidney; transplantation; kidney transplantation; effect human ... See more keywords
Insights into the effect of human civilization on Malus evolution and domestication.
Sign Up to like & getrecommendations! Published in 2021 at "Plant biotechnology journal"
DOI: 10.1111/pbi.13648
Abstract: The evolutionary history of the Malus genus has not been well studied. In the current study, we presented genetic evidence on the origin of the Malus genus based on genome sequencing of 297 Malus accessions,… read more here.
Keywords: effect human; insights effect; domestication; malus ... See more keywords
Effect of Human Synovial Fluid From Osteoarthritis Patients and Healthy Individuals On Lymphatic Contractile Activity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4053749
Abstract: The lymphatic system has been proposed to play a crucial role in preventing the development and progression of osteoarthritis (OA). As OA develops and progresses, inflammatory cytokines and degradation by-products of joint tissues build up… read more here.
Keywords: osteoarthritis; healthy individuals; effect human; treatment ... See more keywords
Does glucagon have a positive inotropic effect in the human heart?
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-018-0791-z
Abstract: Glucagon is considered to exert cardiostimulant effects, most notably the enhancement of heart rate and contractility, due to the stimulation of glucagon receptors associated with Gs protein stimulation which causes adenylyl cyclase activation and the… read more here.
Keywords: effect human; glucagon; heart; positive inotropic ... See more keywords
Effect of Human-Induced Environmental Changes on Bird Diversity and Abundance in Natural Wetlands of Southwest Ethiopia
Sign Up to like & getrecommendations! Published in 2017 at "Waterbirds"
DOI: 10.1675/063.040.0205
Abstract: Abstract. The diversity and abundance of wetland birds have been threatened by increasing anthropogenic activities during recent decades. The objective of this study was to determine the effect of human-induced disturbance on bird species richness… read more here.
Keywords: effect human; human induced; abundance natural; species richness ... See more keywords
The Effect of Human Development Index on Obesity Prevalence at the Global Level: A Spatial Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v52i4.12456
Abstract: Background: Obesity is one of the major public health concerns, and its prevalence is increasing worldwide. This study aimed to investigate the effect of human development index on the prevalence of obesity across 152 countries.… read more here.
Keywords: effect human; prevalence; human development; obesity ... See more keywords
Corrigendum: Effect for Human Genomic Variation During the BMP4-Induced Conversion From Pluripotent Stem Cells to Trophoblast
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.00538
Abstract: [This corrects the article DOI: 10.3389/fgene.2020.00230.]. read more here.
Keywords: effect human; variation bmp4; corrigendum effect; human genomic ... See more keywords