Prophylactic potential of memantine against soman poisoning in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology"
DOI: 10.1016/j.tox.2019.01.012
Abstract: BACKGROUND Carbamates physostigmine and pyridostigmine have been used as a pretreatment against poisoning with nerve agents in order to reversibly inhibit and thus protect from irreversible inhibition a portion of acetylcholinesterase (AChE) in brain and… read more here.
Keywords: effect memantine; soman poisoning; soman; poisoning rats ... See more keywords
Antitumor effect of memantine is related to the formation of the splicing isoform of GLG1, a decoy FGF‑binding protein.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of oncology"
DOI: 10.3892/ijo.2022.5370
Abstract: Drug repositioning is a strategy for repurposing the approved or investigational drugs that are outside the scope of the original medical indication. Memantine is used as a non‑competitive N‑methyl‑D‑aspartate receptor antagonist to prevent glutamate‑mediated excitotoxicity… read more here.
Keywords: glg1; decoy fgf; effect memantine; memantine related ... See more keywords