Effect Modification between Genes and Environment and Parkinson's Disease Risk
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26467
Abstract: Parkinson's disease (PD) is a complex neurodegenerative condition in which genetic and environmental factors interact to contribute to its etiology. Remarkable progress has been made in deciphering disease etiology through genetic approaches, but there is… read more here.
Keywords: disease; modification genes; etiology; parkinson disease ... See more keywords
NAFLD improves risk prediction of type 2 diabetes: with effect modification by sex and menopausal status
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32560
Abstract: The effects of sex and menopausal status on the association between NAFLD and incident type 2 diabetes (T2D) remain unclear. We investigated the effect modification by sex and menopause in the association between NAFLD and… read more here.
Keywords: menopausal status; sex; type diabetes; effect modification ... See more keywords
Network meta‐interpolation: Effect modification adjustment in network meta‐analysis using subgroup analyses
Sign Up to like & getrecommendations! Published in 2022 at "Research Synthesis Methods"
DOI: 10.1002/jrsm.1608
Abstract: Effect modification (EM) may cause bias in network meta‐analysis (NMA). Existing population adjustment NMA methods use individual patient data to adjust for EM but disregard available subgroup information from aggregated data in the evidence network.… read more here.
Keywords: network; effect modification; network meta;
The association of disordered eating with health-related quality of life in U.S. young adults and effect modification by gender
Sign Up to like & getrecommendations! Published in 2020 at "Quality of Life Research"
DOI: 10.1007/s11136-019-02396-2
Abstract: Purpose To examine the relationship of disordered eating behaviors and eating disorder (ED) diagnosis in young adults with health-related quality of life (HRQL) and to assess the presence of effect modification by gender. Methods In… read more here.
Keywords: diagnosis; modification gender; disordered eating; health ... See more keywords
Causal interaction and effect modification: a randomization-based approach to inference
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Korean Statistical Society"
DOI: 10.1007/s42952-025-00313-7
Abstract: Understanding causal interactions is critical in observational studies but often challenging due to confounding and methodological limitations. While these concepts have been extensively studied in randomized experiments, their application in observational data remains limited, particularly… read more here.
Keywords: randomization based; causal interaction; effect modification; interaction effect ... See more keywords
A cross‐sectional study of general cognitive abilities among Uruguayan school children with low‐level arsenic exposure, potential effect modification by methylation capacity and dietary folate
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Research"
DOI: 10.1016/j.envres.2018.02.021
Abstract: Background: Few studies have evaluated the association between low‐level arsenic (As) exposure and cognitive performance among children. Objectives: In this cross‐sectional study, we assessed the association between low‐level As exposure and cognitive performance among 5–8… read more here.
Keywords: folate intake; low level; effect modification;
TUTORIAL: A NONTECHNICAL EXPLANATION OF THE COUNTERFACTUAL DEFINITION OF EFFECT MODIFICATION AND INTERACTION.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2021.01.022
Abstract: Effect modification and interaction are important concepts for answering causal questions about interdependent effects of two (or more) exposures on some outcome of interest. Although conceptually alike and often mistakenly regarded as synonymous, effect modification… read more here.
Keywords: effect; modification interaction; effect modification; nontechnical explanation ... See more keywords
Effect modification and non-collapsibility together may lead to conflicting treatment decisions: A review of marginal and conditional estimands and recommendations for decision-making
Sign Up to like & getrecommendations! Published in 2025 at "Research Synthesis Methods"
DOI: 10.1017/rsm.2025.2
Abstract: Effect modification occurs when a covariate alters the relative effectiveness of treatment compared to control. It is widely understood that, when effect modification is present, treatment recommendations may vary by population and by subgroups within… read more here.
Keywords: effect modification; population; decision making; effect ... See more keywords
Effect Modification of Selenium Supplementation by Intake and Serum Concentrations of Antioxidants on the Development of Metachronous Colorectal Adenoma
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2135745
Abstract: Abstract Background Selenium (Se) is a trace element that has been investigated as a potential chemopreventive agent for colorectal cancer. Dietary intake of other antioxidant nutrients may modify the effect of Se. Objective We examined… read more here.
Keywords: development metachronous; effect modification; effect; selenium supplementation ... See more keywords
Effect Modification by Age on the Benefit or Harm of Antihypertensive Treatment for Elderly Hypertensives: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hypertension"
DOI: 10.1093/ajh/hpy169
Abstract: BACKGROUND The influence of age on balance of benefit vs. potential harm of blood pressure (BP)-lowering therapy for elderly hypertensives is unclear. We evaluated the modifying effects of age on BP lowering for various adverse… read more here.
Keywords: risk; elderly hypertensives; age; analysis ... See more keywords
Interaction and Effect Modification in the Association between Socioeconomic Status and Adolescent Smoking: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2025 at "Epidemiologic reviews"
DOI: 10.1093/epirev/mxaf013
Abstract: This systematic review aimed to identify effect modification and interaction factors that moderate the association between socioeconomic status (SES) and smoking behavior among adolescents. We searched PubMed, Embase, PsycINFO, and Web of Science using keywords… read more here.
Keywords: effect modification; interaction; association; review ... See more keywords