Pharmacological evidences that the inhibitory effects of prostaglandin E2 are mediated by the EP2 and EP4 receptors in human neutrophils.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiae029
Abstract: Prostaglandin (PG) E2 is a recognized inhibitor of granulocyte functions. However, most of the data supporting this was obtained when available pharmacological tools mainly targeted the EP2 receptor. Herein, we revisited the inhibitory effect of… read more here.
Keywords: receptor; human neutrophils; effect pge2; ep2 ep4 ... See more keywords
Regulatory effect of PGE2 on microbicidal activity and inflammatory cytokines in canine leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Parasite Immunology"
DOI: 10.1111/pim.12713
Abstract: Canine leishmaniasis (CanL) is caused by the intracellular parasite Leishmania infantum. Prostaglandin E2 (PGE2) exerts potent regulatory effects on the immune system in experimental model Leishmania infection, but this influence has not yet been studied… read more here.
Keywords: effect pge2; pge2; regulatory effect; canine leishmaniasis ... See more keywords