GW29-e0161 Effect of Pioglitazone on the Development of Atherosclerosis and its Underlying Mechanisms in Diabetic Apolipoprotein E-Null Mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.027
Abstract: This study aimed to investigate the effects of a PPAR-γ agonist pioglitazone on atherogenesis in a ApoE knockout mice (ApoE-/-) diabetic mice model and cultured vascular smooth muscle cells (VSMCs) model. At the same time,… read more here.
Keywords: effect pioglitazone; development atherosclerosis; pioglitazone development; gw29 e0161 ... See more keywords
PI3K/AKT/JNK/p38 signalling pathway‐mediated neural apoptosis in the prefrontal cortex of mice is involved in the antidepressant‐like effect of pioglitazone
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12918
Abstract: Numerous studies have reported that inflammation is involved in the pathophysiology of depression. Pioglitazone, a PPAR‐γ agonist, has potential anti‐inflammatory and antidepressive effects. However, the underlying molecular mechanisms of the antidepressant‐like effect of pioglitazone on… read more here.
Keywords: effect pioglitazone; pioglitazone; like effect; jnk p38 ... See more keywords