The effect of point mutations on the biophysical properties of an anti-microbial peptide: development of a screening protocol for peptide stability screening.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00406
Abstract: Therapeutic peptides and proteins show an enormous potential on the pharmaceutical market, but high costs in discovery and development are limiting factors so far. Single or multiple point mutations are commonly introduced in protein drugs… read more here.
Keywords: peptide; point mutations; effect point; stability ... See more keywords
Investigation of the effect of point defects on the Li-ion conductivity of Li3InCl6.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt02943j
Abstract: The effect of point defects on the performance of the Li3InCl6 solid electrolyte was investigated using first-principles simulations. The Li-ion conductivity of Li3InCl6 was improved by the presence of point defects, such as a 4g… read more here.
Keywords: ion conductivity; effect point; point defects; li3incl6 ... See more keywords
Simulation of the Effect of Point Mutations on the Stability of Protein Dimers Using the Bcl-2 Protein Family as an Example
Sign Up to like & getrecommendations! Published in 2020 at "Technical Physics"
DOI: 10.1134/s1063784220040131
Abstract: Abstract A new method has been developed that enables synthesizing peptides with desired physicochemical properties, for example, with high affinity to one target protein and low affinity to other proteins, and determining the stability of… read more here.
Keywords: stability protein; effect point; example; family ... See more keywords
What effect do point of care fees have on childhood consultations in general practice?
Sign Up to like & getrecommendations! Published in 2018 at "BMC Health Services Research"
DOI: 10.1186/s12913-018-3800-8
Abstract: BackgroundGeneral practice (GP) has historically been central to the prevention and treatment of childhood illnesses. In Ireland, this role has recently expanded with the introduction of free GP care for children aged under six years… read more here.
Keywords: general practice; fees childhood; point care; effect point ... See more keywords