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Published in 2022 at "Current drug metabolism"
DOI: 10.2174/1389200223666220215151945
Abstract: BACKGROUND Significant inter-subject variability in pharmacokinetics and clinical outcomes has been observed for the antimalarial agent piperaquine (PQ). PQ is metabolized by CYP3A4, mainly regulated by pregnane X receptor (PXR). CYP3A4(*1B) polymorphism did not affect…
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Keywords:
8055c polymorphism;
pxr 8055c;
effect pxr;
pharmacokinetic profiles ... See more keywords