Ameliorate effect of pyrroloquinoline quinone against cyclophosphamide-induced nephrotoxicity by activating the Nrf2 pathway and inhibiting the NLRP3 pathway.
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DOI: 10.1016/j.lfs.2020.117901
Abstract: AIMS Cyclophosphamide (CTX) is an effective anti-tumor and immunosuppressive agent, but it induces nephrotoxicity in clinical applications. The present study aimed to evaluate the protective effect of pyrroloquinoline quinone (PQQ) on CTX-induced nephrotoxicity. MAIN METHODS… read more here.
Keywords: pyrroloquinoline quinone; induced nephrotoxicity; effect pyrroloquinoline; activating nrf2 ... See more keywords