Effect of sitagliptin on diabetes-induced hyperpermeability of blood-retinal barrier components
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DOI: 10.1038/s41433-025-03924-w
Abstract: The important role of neurodegeneration in the pathogenesis of diabetic retinal disease (DRD) and the evidence that several neuroprotective retinal factors are downregulated in diabetes have led to propose replacement treatment via eyedrops of these… read more here.
Keywords: hyperpermeability; retinal barrier; effect sitagliptin; blood retinal ... See more keywords
Abstract P328: Effect of Sitagliptin on the Hemodynamic and Metabolic Response to a Mixed Meal in Individuals With Type 2 Diabetes and Hypertension
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DOI: 10.1161/hyp.72.suppl_1.p328
Abstract: Dipeptidyl peptidase IV (DPP4) inhibitors such as sitagliptin are anti-diabetes drugs that may also have cardiovascular effects. We tested the hypothesis that there is an interactive effect between... read more here.
Keywords: hypertension abstract; effect; p328 effect; hypertension ... See more keywords
Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity
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DOI: 10.1371/journal.pone.0174295
Abstract: Sitagliptin is selective dipeptidyl peptidase-4 inhibitor (DPP4-I), used clinically as a new oral anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective role of sitagliptin pretreatment against methotrexate (MTX) induced hepatotoxicity in mice.… read more here.
Keywords: methotrexate; hepatoprotective effect; sitagliptin; mtx ... See more keywords