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Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05451-w
Abstract: Rationale Barriers to smoking cessation, including negative affect and cognitive dysfunction, may contribute to high smoking rates among people living with HIV/AIDS (PLWH). Varenicline may help PLWH quit smoking by improving mood and cognition, yet…
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Keywords:
varenicline mood;
varenicline;
effect varenicline;
mood cognition ... See more keywords
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Published in 2018 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000355
Abstract: Nicotinic acetylcholine receptors (nAChRs) are implicated in the pathogenesis of Parkinson’s disease (PD). Varenicline tartrate is a partial agonist at &agr;4&bgr;2 and full agonist at &agr;7 neuronal nAChR subunits. A unilateral lesion of the substantia…
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Keywords:
lesion substantia;
behavioral deficits;
substantia nigra;
effect varenicline ... See more keywords
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Published in 2021 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2021.19.2.355
Abstract: Objective Although evidence implicates striatal cholinergic impairment as a mechanism underlying tardive dyskinesia, trials of nonspecific cholinergic agents have been inconclusive. As a partial agonist at specific nicotinic receptor subtypes, varenicline reduces drug-induced dyskinesias in…
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Keywords:
effect varenicline;
dyskinesia;
tardive dyskinesia;
varenicline tardive ... See more keywords