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Published in 2023 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00583
Abstract: Adjuvants are essential for the induction of robust immune responses against vaccine antigens. Small-molecule TLR7 agonists hold high potential for this purpose. In this communication, imiquimod (IMQ) bearing a cholesterol lipid moiety derivative, IMQ-Chol, was…
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Keywords:
effective adjuvant;
lipidized imiquimod;
formulation evaluation;
imq chol ... See more keywords
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2
Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11030649
Abstract: Current influenza vaccines mainly induce neutralizing antibodies against the highly variable surface antigen hemagglutinin and require annual manufacturing and immunization. Different from surface antigens, intracellular nucleoprotein (NP) is highly conserved and has been an attractive…
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Keywords:
immunization;
cpg 1018;
effective adjuvant;
influenza ... See more keywords