Amphiphilic Dendrimer Doping Enhanced pH‐Sensitivity of Liposomal Vesicle for Effective Co‐delivery toward Synergistic Ferroptosis–Apoptosis Therapy of Hepatocellular Carcinoma
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DOI: 10.1002/adhm.202202663
Abstract: Ferroptosis, characterized by the accumulation of reactive oxygen species and lipid peroxides, has emerged as an attractive strategy to reverse drug resistance. Of particular interest is the ferroptosis–apoptosis combination therapy for cancer treatment. Herein, a… read more here.
Keywords: apoptosis; therapy; effective delivery; ferroptosis ... See more keywords
Effective delivery of volatile biocides employing mesoporous silicates for treating biofilms
Sign Up to like & getrecommendations! Published in 2017 at "Journal of The Royal Society Interface"
DOI: 10.1098/rsif.2016.0650
Abstract: Nanoparticulate delivery of biocides has the potential to decrease levels of exposure to non-target organisms, and miminize long-term exposure that can promote the development of resistance. Silica nanoparticles are an ideal vehicle since they are… read more here.
Keywords: volatile biocides; effective delivery; employing mesoporous; biocides employing ... See more keywords
Safe and Effective Delivery of Amphotericin B: A Survey of Patents.
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DOI: 10.2174/1872210511666170105130210
Abstract: BACKGROUND Amphotericin B, designated as the gold standard among antifungal drugs is the only fungicidal effective against systemic fungal infections. But this drug has various pitfalls associated with it, to bypass which various techniques have… read more here.
Keywords: amphotericin; effective delivery; delivery; drug ... See more keywords
Enhancing Molecular Testing for Effective Delivery of Actionable Gene Diagnostics
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DOI: 10.3390/bioengineering9120745
Abstract: There is a deep need to navigate within our genomic data to find, understand and pave the way for disease-specific treatments, as the clinical diagnostic journey provides only limited guidance. The human genome is enclosed… read more here.
Keywords: molecular testing; testing effective; phenotype; enhancing molecular ... See more keywords
Dextran Formulations as Effective Delivery Systems of Therapeutic Agents
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DOI: 10.3390/molecules28031086
Abstract: Dextran is by far one of the most interesting non-toxic, bio-compatible macromolecules, an exopolysaccharide biosynthesized by lactic acid bacteria. It has been extensively used as a major component in many types of drug-delivery systems (DDS),… read more here.
Keywords: dextran formulations; dextran; delivery systems; formulations effective ... See more keywords
Safe and Effective Delivery of mRNA Using Modified PEI-Based Lipopolymers
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DOI: 10.3390/pharmaceutics15020410
Abstract: Chemically modified mRNA (modRNA) has proven to be a versatile tool for the treatment of various cancers and infectious diseases due to recent technological advancements. However, a safe and effective delivery system to overcome the… read more here.
Keywords: delivery mrna; effective delivery; safe effective; delivery ... See more keywords