LAUSR

Effective regeneration of dystrophic muscle using autologous iPSC-derived progenitors with CRISPR-Cas9 mediated precise correction.

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0 Published in 2018 at "Medical hypotheses"

DOI: 10.1016/j.mehy.2017.11.009

Abstract: Duchenne muscular dystrophy (DMD) is a lethal muscle wasting disease caused by a lack of dystrophin, which eventually leads to apoptosis of muscle cells and impaired muscle contractility. Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated… read more here.

Keywords: muscle; crispr cas9; effective regeneration; ipsc ... See more keywords