A drug‐repositioning screen for primary pancreatic ductal adenocarcinoma cells identifies 6‐thioguanine as an effective therapeutic agent for TPMT‐low cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12364
Abstract: Pancreatic cancer is one of the most difficult cancers to cure due to the lack of early diagnostic tools and effective therapeutic agents. In this study, we aimed to isolate new bioactive compounds that effectively… read more here.
Keywords: therapeutic agent; ductal adenocarcinoma; pancreatic ductal; cancer cells ... See more keywords
Polyphenols as an Effective Therapeutic Intervention Against Cognitive Decline During Normal and Pathological Brain Aging.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-42667-5_7
Abstract: Research in animals and humans has indicated that polyphenols can delay the age-related decline in learning, memory and neurodegenerative diseases. Among the polyphenols, berry phenolics have extensive beneficial effects because of their antioxidant and anti-inflammatory… read more here.
Keywords: decline; therapeutic intervention; polyphenols effective; effective therapeutic ... See more keywords
Imatinib as a potentially effective therapeutic alternative in corticosteroid‐resistant eosinophilic fasciitis
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Dermatology"
DOI: 10.1111/pde.14327
Abstract: Eosinophilic fasciitis (EF) is a rare condition in children that is typically treated with systemic corticosteroids. We present the case of a 9‐year‐old boy with biopsy‐proven EF, refractory to systemic corticosteroids and methotrexate. The tyrosine… read more here.
Keywords: fasciitis; imatinib potentially; eosinophilic fasciitis; potentially effective ... See more keywords
The potential of interleukin-37 as an effective therapeutic agent in asthma
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DOI: 10.1186/s12931-017-0675-x
Abstract: Interleukin (IL)-37 belongs to the IL-1 cytokine family. It binds to IL-18Rα and recruits the orphan decoy IL-1R8. Emerging evidence shows that IL-37 is a key player in the regulation of inflammation, cellular differentiation, and… read more here.
Keywords: inflammation; inflammatory; effective therapeutic; asthma ... See more keywords
Exercise and Bariatric Surgery: An Effective Therapeutic Strategy
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DOI: 10.1249/jes.0000000000000168
Abstract: Exercise is a clinically effective adjunct therapy with the potential to promote long-term weight loss maintenance for bariatric surgery patients. read more here.
Keywords: bariatric surgery; effective therapeutic; surgery effective; exercise ... See more keywords
HLA-G in asthma and its potential as an effective therapeutic agent.
Sign Up to like & getrecommendations! Published in 2023 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v51i1.650
Abstract: OBJECTIVE Asthma is a heterogeneous disease. Severity of asthma and sensitivity to medications vary across asthma subtypes. Human leukocyte antigen (HLA)-G has a wide range of functions in normal and pathological physiology. Due to its… read more here.
Keywords: hla; effective therapeutic; hla asthma; asthma potential ... See more keywords
Effective Therapeutic Options for Melioidosis: Antibiotics versus Phage Therapy
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DOI: 10.3390/pathogens12010011
Abstract: Melioidosis, also known as Whitmore’s disease, is a potentially fatal infection caused by the Gram-negative bacteria Burkholderia pseudomallei with a mortality rate of 10–50%. The condition is a “glanders-like” illness prevalent in Southeast Asian and… read more here.
Keywords: effective therapeutic; phage therapy; therapy; treatment ... See more keywords