Articles with "effectiveness genotype" as a keyword



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Effectiveness of Genotype-Specific Tricyclic Antidepressant Dosing in Patients With Major Depressive Disorder

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Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.12443

Abstract: Key Points Question Does pharmacogenetics-informed (CYP2D6 and CYP2C19 genotypes) dosing of tricyclic antidepressants result in faster attainment of therapeutic plasma concentrations, higher effectiveness, and fewer and less severe adverse effects compared with usual treatment? Findings… read more here.

Keywords: effectiveness genotype; depressive disorder; patients major; major depressive ... See more keywords