Implementing Immune Effector Cell Education for Nursing Staff
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.476
Abstract: Topic Significance & Study Purpose/Background/Rationale Immune effector cell therapy (IECT) has recently emerged as a revolutionary treatment approach for several hematologic malignancies but is associated with unique administration and management considerations. With the growing number… read more here.
Keywords: cancer; education; immune effector; class ... See more keywords
Immune Effector Cell Associated Neurotoxicity (ICANS) Among Pediatric and AYA Patients: MD Anderson Cancer Center Experience
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.397
Abstract: Introduction Immune effector cell associated neurotoxicity (ICANS) and cytokine release syndrome (CRS) are unique potentially life-threatening complications associated with immune effector cell (IEC) therapies. ICANS presents with varying symptoms ranging from confusion to seizure and… read more here.
Keywords: cell; aya patients; pediatric aya; immune effector ... See more keywords
Multifocal demyelinating leukoencephalopathy and oligodendroglial lineage cell loss with immune effector cell-associated neurotoxicity syndrome (ICANS) following CD19 CAR T-cell therapy for mantle cell lymphoma.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlac121
Abstract: Immune effector cell-associated neurotoxicity syndrome (ICANS) is a prevalent condition seen after treatment with chimeric antigen receptor T-cell (CAR T) therapy and other cancer cell therapies. The underlying pathophysiology and neuropathology of the clinical syndrome… read more here.
Keywords: cell; cell associated; therapy; car ... See more keywords
THU0031 ABATACEPT ALTERS THE FREQUENCY OF IMMUNOREGULATORY AND EFFECTOR T CELL SUBPOPULATIONS IN RHEUMATOID ARTHRITIS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.4894
Abstract: Under physiological conditions, T regulatory cells (Tregs) are responsible for the downregulation of the immune response. In autoimmune diseases, such as rheumatoid arthritis (RA), auto-inflammation is driven by an imbalance of activation and downregulation of… read more here.
Keywords: patients receiving; treatment; cell; effector cell ... See more keywords
The Mechanisms of Effector Th Cell Responses Contribute to Treg Cell Function: New Insights into Pathogenesis and Therapy of Asthma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.862866
Abstract: CD4 + helper T (Th) cell subsets are critically involved in the pathogenesis of asthma. Naive Th cells differentiate into different subsets under the stimulation of different sets of cytokines, and the differentiation process is… read more here.
Keywords: cell; function; treg; treg cell ... See more keywords
A systematic framework for predictive biomarkers in immune effector cell-associated neurotoxicity syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1110647
Abstract: Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the management of several life-threatening malignancies, often achieving durable sustained responses. The number of patients treated with this new class of cell-based therapy, along with the number… read more here.
Keywords: predictive biomarkers; cell; cell associated; associated neurotoxicity ... See more keywords
Modification of Regulatory T Cell Epitopes Promotes Effector T Cell Responses to Aspartyl/Asparaginyl β-Hydroxylase
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012444
Abstract: Cancer is a leading cause of death worldwide. The search for innovative therapeutic approaches is a principal focus of medical research. Vaccine strategies targeting a number of tumor-associated antigens are currently being evaluated. To date,… read more here.
Keywords: cell; aspartyl asparaginyl; asparaginyl hydroxylase; regulatory cell ... See more keywords