Malaria Parasite Translocon Structure and Mechanism of Effector Export
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DOI: 10.1038/s41586-018-0469-4
Abstract: The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of malarial effector proteins across a parasite-encasing vacuolar membrane into host erythrocytes, but the mechanism of this process remains unknown. Here we show… read more here.
Keywords: mechanism; microscopy; effector export; effector ... See more keywords
Toxoplasma chitinase-like protein orchestrates cyst wall glycosylation to facilitate effector export and cyst turnover
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2416870122
Abstract: Significance Chronic infections often involve pathogens in energy-conserving and immune-evading states. Toxoplasma gondii remains semidormant as bradyzoites in tissue cysts within muscles and neurons. The turnover of bradyzoite cysts, including cyst wall remodeling, is crucial… read more here.
Keywords: cyst; export cyst; effector export; cyst wall ... See more keywords