Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2204332119
Abstract: Significance Enteropathogenic Escherichia coli (EPEC) is a significant cause of diarrhea among children in lower income countries. A defining feature of EPEC infection is the formation of attaching and effacing lesions on enterocytes that are… read more here.
Keywords: effector kinases; microvillus protein; protein eps8; targeting microvillus ... See more keywords
Bacterial effector kinases and strategies to identify their target host substrates
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1113021
Abstract: Post-translational modifications (PTMs) are critical in regulating protein function by altering chemical characteristics of proteins. Phosphorylation is an integral PTM, catalyzed by kinases and reversibly removed by phosphatases, that modulates many cellular processes in response… read more here.
Keywords: bacterial effector; effector kinases; host; phosphorylation ... See more keywords