Genome analysis of two novel Pseudomonas strains exhibiting differential hypersensitivity reactions on tobacco seedlings reveals differences in nonflagellar T3SS organization and predicted effector proteins
Sign Up to like & getrecommendations! Published in 2018 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.553
Abstract: Multilocus sequence analysis (MLSA) of two new biological control strains (S1E40 and S3E12) of Pseudomonas was performed to assess their taxonomic position relative to close lineages, and comparative genomics employed to investigate whether these strains… read more here.
Keywords: analysis; s3e12; nonflagellar t3ss; effector proteins ... See more keywords
Prediction of effector proteins and their implications in pathogenicity of phytopathogenic filamentous fungi: A review.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.02.133
Abstract: Plant pathogenic fungi encode and secrete effector proteins to promote pathogenesis. In recent years, the important role of effector proteins in fungi and plant host interactions has become increasingly prominent. In this review, the functional… read more here.
Keywords: proteins implications; implications pathogenicity; prediction effector; plant ... See more keywords
Structural analyses of inositol phosphate second messengers bound to signaling effector proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2019.100667
Abstract: The higher-order inositol phosphate second messengers inositol tetrakisphosphate (IP4), inositol pentakisphosphate (IP5) and inositol hexakisphosphate (IP6) are important signaling molecules that regulate DNA-damage repair, cohesin dynamics, RNA-editing, retroviral assembly, nuclear transport, phosphorylation, acetylation, crotonylation, and… read more here.
Keywords: inositol; inositol phosphate; second messengers; effector proteins ... See more keywords
Effector Biology of Biotrophic Plant Fungal Pathogens: Current Advances and Future Prospects.
Sign Up to like & getrecommendations! Published in 2020 at "Microbiological research"
DOI: 10.1016/j.micres.2020.126567
Abstract: The interaction of fungal pathogens with their host requires a novel invading mechanism and the presence of various virulence-associated components responsible for promoting the infection. The small secretory proteins, explicitly known as effector proteins, are… read more here.
Keywords: effector proteins; biology; host; fungal pathogens ... See more keywords
Post-translational Mechanisms of Host Subversion by Bacterial Effectors.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2017.10.003
Abstract: Bacterial effector proteins are a specialized class of secreted proteins that are translocated directly into the host cytoplasm by bacterial pathogens. Effector proteins have diverse activities and targets, and many mediate post-translational modifications of host… read more here.
Keywords: translational mechanisms; post translational; effector proteins; host ... See more keywords
Cell-Penetrating Bacterial Effector Proteins: Better Tools than Targets.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2016.08.002
Abstract: Bacterial pathogens have developed intriguing virulence mechanisms, including several sophisticated nanomachines, for injecting effector proteins to manipulate host immune signaling pathways for their own benefit. Therefore, bacterial genomes harbor a wealth of information about how… read more here.
Keywords: bacterial effector; cell penetrating; effector proteins; penetrating bacterial ... See more keywords
Observing protein interaction dynamics to chemically defined chromatin fibers by colocalization single-molecule fluorescence microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods"
DOI: 10.1016/j.ymeth.2020.01.018
Abstract: In eukaryotic cells, the genome is packaged into chromatin and exists in different states, ranging from open euchromatic regions to highly condensed heterochromatic regions. Chromatin states are highly dynamic and are organized by an interplay… read more here.
Keywords: fluorescence; microscopy; chromatin; effector proteins ... See more keywords
LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44598
Abstract: Pathogens secrete effector proteins and many operate inside plant cells to enable infection. Some effectors have been found to enter subcellular compartments by mimicking host targeting sequences. Although many computational methods exist to predict plant… read more here.
Keywords: plant; subcellular localization; effector proteins; plant effector ... See more keywords
Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122872119
Abstract: Significance Mitochondria are organelles of the central metabolism that produce ATP and play fundamental roles in eukaryotic cell function and thereby become targets for pathogenic bacteria to manipulate. We found that the intracellular bacterial pathogen,… read more here.
Keywords: effector proteins; mitochondrial adp; atp translocases; adp atp ... See more keywords
Pathogens manipulate host autophagy through injected effector proteins
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1831816
Abstract: ABSTRACT Macroautophagy/autophagy plays a dual role in many physiological processes of multicellular eukaryotes. In plants, autophagy can be used by both host and pathogen for a beneficiary infection outcome. Plants employ a two-tier innate immune… read more here.
Keywords: triggered immunity; effector proteins; autophagy; host ... See more keywords
Usurping bacterial virulence factors as self-delivery vehicles for therapeutic use
Sign Up to like & getrecommendations! Published in 2017 at "Virulence"
DOI: 10.1080/21505594.2017.1336595
Abstract: Type III secretion systems (T3SS) as virulence factors were initially discovered in Yersinia and are now widely recognized in many bacterial pathogens that infect animals and plants. It was observed about 20 y ago that… read more here.
Keywords: t3ss; virulence; delivery; virulence factors ... See more keywords