Epistatic Effects Between Amino Acid Insertions and Substitutions Mediate Toxin resistance of Vertebrate Na+,K+-ATPases
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac258
Abstract: The recurrent evolution of resistance to cardiotonic steroids (CTS) across diverse animals most frequently involves convergent amino-acid substitutions to the H1-H2 extracellular loop of Na+,K+-ATPase (NKA). Previous work established that hystricognath rodents (e.g. chinchilla) and… read more here.
Keywords: effects amino; acid insertions; resistance; amino acid ... See more keywords
Peptide framework for screening the effects of amino acids on assembly
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abj0305
Abstract: Discovery of peptide domains with unique intermolecular interactions is essential for engineering peptide-based materials. Rather than attempting a brute-force approach, we instead identify a previously unexplored strategy for discovery and study of intermolecular interactions: “co-assembly… read more here.
Keywords: effects amino; framework screening; framework; peptide ... See more keywords
Biostimulatory Effects of Amino Acids on Phenylalanine Ammonia Lyase, Capsaicin Synthase, and Peroxidase Activities in Capsicum baccatum L.
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11050674
Abstract: Simple Summary Very little is known about how biostimulants such as amino acids affect the enzymatic activity of peppers. The three crucial enzymes for the synthesis and degradation of capsaicinoids were studied in a 72… read more here.
Keywords: application; amino acids; biostimulatory effects; effects amino ... See more keywords
Investigating the Effects of Amino Acid Variations in Human Menin
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051747
Abstract: Human menin is a nuclear protein that participates in many cellular processes, as transcriptional regulation, DNA damage repair, cell signaling, cell division, proliferation, and migration, by interacting with many other proteins. Mutations of the gene… read more here.
Keywords: effects amino; amino acid; human menin; investigating effects ... See more keywords
Theoretical Analysis of the Dynamical Effects of the Amino Acid Residue Replacement in the Vicinity of the [4Fe–4S] Proximal Cluster on the O2-Tolerance of [NiFe]-Hydrogenases
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Physical Society of Japan"
DOI: 10.7566/jpsj.90.034804
Abstract: Hydrogenases are enzymes that catalyze the reversible reaction, \(\text{H}_{2} \rightleftharpoons 2\text{H}^{ + } + 2\text{e}^{ - }\), that occurs at the transition metal cluster in the catalytic c... read more here.
Keywords: theoretical analysis; cluster; analysis dynamical; effects amino ... See more keywords