Protective effects of apigenin on altered lipid peroxidation, inflammation, and antioxidant factors in methotrexate-induced hepatotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's archives of pharmacology"
DOI: 10.1007/s00210-020-01991-2
Abstract: Methotrexate (MTX) is used as an effective chemotherapeutic agent against autoimmune diseases and tumors. Oxidative stress and inflammation are involved in the pathogenesis of MTX-induced damage. This study aimed at examining the ameliorating effects of… read more here.
Keywords: induced hepatotoxicity; group; inflammation; mtx induced ... See more keywords
Effects of apigenin, hesperidin and their combinations on different physiopathological pathways in 5-fluorouracil-induced pulmonary damage.
Sign Up to like & getrecommendations! Published in 2025 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2025.2531443
Abstract: BACKGROUND Chemotherapeutics target cancerous cells, but they also have unavoidable toxicities in healthy tissues. AIM In this study, the effects of the commonly used chemotherapeutic 5-fluorouracil (5FU) on lung tissue were investigated, along with the… read more here.
Keywords: effects apigenin; combinations different; api hes; fluorouracil ... See more keywords
Effects of Apigenin on the apoptosis index of atherosclerosis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001736
Abstract: Recently, Apigenin has been widely studied for its anti-atherosclerosis properties, but its mechanism remains to be further elucidated.This study aims to evaluate the expression of LOX-1, Bcl-2 and Bax in apigenin-treated atherosclerotic rats and to… read more here.
Keywords: effects apigenin; apoptosis index; index atherosclerosis; atherosclerosis ... See more keywords
Reactive oxygen species: Key players in the anticancer effects of apigenin?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14060
Abstract: Reactive oxygen species (ROS) exhibit a double-edged sword in cancer-hence their modulation has been an attractive strategy in cancer prevention and therapy. The abundance of scientific information on the pro-oxidant effects of apigenin in cancer… read more here.
Keywords: reactive oxygen; oxygen species; pro oxidant; effects apigenin ... See more keywords
Effects of Apigenin, Luteolin, and Quercetin on the Natural Killer (NK-92) Cells Proliferation: A Potential Role as Immunomodulator
Sign Up to like & getrecommendations! Published in 2021 at "Sains Malaysiana"
DOI: 10.17576/jsm-2021-5003-22
Abstract: Cancer can be classified as a fourth leading cause of death in Malaysia. There is a continuous effort by scientists in finding alternative cure to cancer due to the known side effects of chemotherapy and… read more here.
Keywords: luteolin quercetin; apigenin luteolin; natural killer; killer cells ... See more keywords
Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21134620
Abstract: Apigenin (4′,5,7-trihydroxyflavone, flavonoid) is a phenolic compound that is known to reduce the risk of chronic disease owing to its low toxicity. The first study on apigenin analyzed its effect on histamine release in the… read more here.
Keywords: hacat cells; expression; rbl 2h3; hacat ... See more keywords
Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16060811
Abstract: Apigenin is a phytochemical obtained from Chamomilla recutita. Its role in interstitial cystitis is not yet known. The present study is aimed at understanding the uroprotective and spasmolytic effects of apigenin in cyclophosphamide-induced interstitial cystitis.… read more here.
Keywords: tgf inos; spasmolytic uroprotective; apigenin; effects apigenin ... See more keywords