Therapeutic effects of atorvastatin on doxorubicin-induced hepatotoxicity in rats via antioxidative damage, anti-inflammatory, and anti-lipotoxicity.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23329
Abstract: Doxorubicin (DOX), is a high efficiency anthracycline antitumor drug. However, the clinical application of DOX is limited mainly by dose‐related adverse drug reactions. Currently, the therapeutic effects of Atorvastatin (ATO) on DOX‐induced hepatotoxicity were studied… read more here.
Keywords: therapeutic effects; dox; doxorubicin; effects atorvastatin ... See more keywords
Effects of Atorvastatin on Bile Acid Metabolism in High-Fat Diet-Fed ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001425
Abstract: Abstract Statins are considered as the cornerstone of the prevention and treatment of atherosclerotic cardiovascular disease, where pleiotropic effects are thought to contribute greatly in addition to the lipid-lowering effect. Bile acid metabolism has been… read more here.
Keywords: acid metabolism; effects atorvastatin; high fat; bile acid ... See more keywords
The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13128
Abstract: The present study investigated the effects of atorvastatin on kidney injury in mice with pulmonary fibrosis (PF). read more here.
Keywords: kidney injury; effects atorvastatin; mice pulmonary; injury mice ... See more keywords