Therapeutic effects of atorvastatin on doxorubicin-induced hepatotoxicity in rats via antioxidative damage, anti-inflammatory, and anti-lipotoxicity.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23329
Abstract: Doxorubicin (DOX), is a high efficiency anthracycline antitumor drug. However, the clinical application of DOX is limited mainly by dose‐related adverse drug reactions. Currently, the therapeutic effects of Atorvastatin (ATO) on DOX‐induced hepatotoxicity were studied… read more here.
Keywords: therapeutic effects; dox; doxorubicin; effects atorvastatin ... See more keywords
Effects of Atorvastatin on Bile Acid Metabolism in High-Fat Diet-Fed ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001425
Abstract: Abstract Statins are considered as the cornerstone of the prevention and treatment of atherosclerotic cardiovascular disease, where pleiotropic effects are thought to contribute greatly in addition to the lipid-lowering effect. Bile acid metabolism has been… read more here.
Keywords: acid metabolism; effects atorvastatin; high fat; bile acid ... See more keywords
The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13128
Abstract: The present study investigated the effects of atorvastatin on kidney injury in mice with pulmonary fibrosis (PF). read more here.
Keywords: kidney injury; effects atorvastatin; mice pulmonary; injury mice ... See more keywords
In Vitro Investigation of the Antiproliferative and Antimetastatic Effects of Atorvastatin: A Focus on Cervical and Head and Neck Cancers
Sign Up to like & getrecommendations! Published in 2025 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics17101253
Abstract: Background/Objectives: In spite of substantial treatment progress, cancer persists as a leading health challenge. With the slow advancement in developing new anticancer agents, drug repurposing provides a promising strategy to enhance cancer therapy. This study… read more here.
Keywords: cancer; antimetastatic effects; antiproliferative antimetastatic; effects atorvastatin ... See more keywords
Comparative vasorelaxant effects of atorvastatin and rosuvastatin in rat aorta: investigating the role of perivascular adipose tissue
Sign Up to like & getrecommendations! Published in 2025 at "Turkish Journal of Medical Sciences"
DOI: 10.55730/1300-0144.5996
Abstract: Background/aim Statins are known to display pleiotropic effects on the vascular system, beyond their lipid-lowering properties. Studies on isolated vascular preparations have demonstrated their acute relaxant effects on vascular tone. Considering the increased evidence in… read more here.
Keywords: without pvat; effects atorvastatin; rat; pvat ... See more keywords