The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7539
Abstract: Various factors interfere with the endoplasmic reticulum (ER) function, which is involved in protein folding and calcium homeostasis. ER dysfunction referred to as ER stress triggers cell death by apoptosis and inflammation. Berberine (BBR) is… read more here.
Keywords: endoplasmic reticulum; stress; therapeutic effects; berberine different ... See more keywords
Inhibitory effects of berberine on ovarian cancer: Beyond apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-021-02763-0
Abstract: Ovarian cancer is one of the main causes of women’s mortality worldwide. A variety of biological mechanisms are involved in ovarian cancer pathogenesis, including epigenetic alterations, mutations (especially in tumor suppressor genes), upregulated oncogenes, decreased… read more here.
Keywords: ovarian cancer; cancer beyond; cancer; effects berberine ... See more keywords
The therapeutic effects of berberine for gastrointestinal cancers.
Sign Up to like & getrecommendations! Published in 2023 at "Asia-Pacific journal of clinical oncology"
DOI: 10.1111/ajco.13941
Abstract: Cancer is one of the most serious human health issues. Drug therapy is the major common way to treat cancer. There is a growing interest in using natural compounds to overcome drug resistance, adverse reactions,… read more here.
Keywords: oncology; gastrointestinal cancers; therapeutic effects; effects berberine ... See more keywords
Immunomodulatory effects of berberine on the inflamed joint reveal new therapeutic targets for rheumatoid arthritis management
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15803
Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory syndrome designated by synovial joint inflammation leading to cartilage degradation and bone damage as well as progressive disability. Synovial inflammation is promoted through the infiltration of mononuclear immune… read more here.
Keywords: effects berberine; therapeutic targets; immunomodulatory effects; berberine inflamed ... See more keywords
Research progress on the pharmacological effects of berberine targeting mitochondria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.982145
Abstract: Berberine is a natural active ingredient extracted from the rhizome of Rhizoma Coptidis, which interacts with multiple intracellular targets and exhibits a wide range of pharmacological activities. Previous studies have preliminarily confirmed that the regulation… read more here.
Keywords: regulating mitochondrial; effects berberine; progress pharmacological; mitochondrial activity ... See more keywords
Toxicological Effects of Berberine and Sanguinarine
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DOI: 10.3389/fmolb.2018.00021
Abstract: Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced… read more here.
Keywords: berberine sanguinarine; toxicological effects; effects berberine; sanguinarine ... See more keywords
Cellular and Molecular Mechanisms and Effects of Berberine on Obesity-Induced Inflammation
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DOI: 10.3390/biomedicines10071739
Abstract: Obesity represents chronic low-grade inflammation that precipitates type 2 diabetes, cardiovascular disease, and cancer. Berberine (BBR) has been reported to exert anti-obesity and anti-inflammatory benefits. We aimed to demonstrate the underlying immune-modulating mechanisms of anti-obesity… read more here.
Keywords: inflammation; mechanisms effects; molecular mechanisms; effects berberine ... See more keywords
Effects of Berberine against Pancreatitis and Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238630
Abstract: The pancreas is a glandular organ with endocrine and exocrine functions necessary for the maintenance of blood glucose homeostasis and secretion of digestive enzymes. Pancreatitis is characterized by inflammation of the pancreas leading to temporary… read more here.
Keywords: pancreatic cancer; effects berberine; berberine pancreatitis; pancreatitis pancreatic ... See more keywords