Opposing and potentially antagonistic effects of BMP and TGF-β in multiple sclerosis: The “Yin and Yang” of neuro-immune Signaling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2020.577358
Abstract: Bone Morphogenetic Proteins (BMP) and Transforming Growth Factor-beta (TGF-β) are cytokines with similar receptors and messengers. They are important for immune cell function, with BMPs exerting mainly proinflammatory but also anti-inflammatory effects, and TGF-β suppressing… read more here.
Keywords: sclerosis; effects bmp; potentially antagonistic; multiple sclerosis ... See more keywords
LAPONITE® nano-silicates potentiate the angiogenic effects of FG-4592 and osteogenic effects of BMP-2.
Sign Up to like & getrecommendations! Published in 2024 at "Biomaterials science"
DOI: 10.1039/d4bm00636d
Abstract: LAPONITE®-based drug delivery systems offer many advantages due to the unique ionic and physical properties of LAPONITE®. The high ionicity and large surface area of LAPONITE® nanoparticles enable the intercalation and dissolution of biomolecules. In… read more here.
Keywords: effects bmp; osteogenic effects; laponite nano; silicates potentiate ... See more keywords