Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks
Sign Up to like & getrecommendations! Published in 2022 at "Proteomics"
DOI: 10.1002/pmic.202100247
Abstract: Fingolimod (FTY720) is an oral drug approved by the Food and Drug Administration (FDA) for management of multiple sclerosis (MS) symptoms, which has also shown beneficial effects against Alzheimer's (AD) and Parkinson's (PD) diseases pathologies.… read more here.
Keywords: effects brain; fingolimod effects; modulation; fingolimod treated ... See more keywords
Assessing the joint effects of brain aging and gut microbiota on the risks of psychiatric disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Brain imaging and behavior"
DOI: 10.1007/s11682-022-00630-z
Abstract: We aim to explore the potential interaction effects of brain aging and gut microbiota on the risks of sleep, anxiety and depression disorders. The genome-wide association study (GWAS) datasets of brain aging (N = 21,407) and gut… read more here.
Keywords: gut microbiota; aging gut; brain aging; effects brain ... See more keywords
Stress hormones as potential mediators of air pollutant effects on the brain: Rapid induction of glucocorticoid-responsive genes.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental research"
DOI: 10.1016/j.envres.2019.108717
Abstract: Air pollution is associated with adverse effects on brain health including cognitive decline, dementia, anxiety, depression, and suicide. While toxicological studies have demonstrated the potential for repeated or chronic pollutant exposure to lead to disease… read more here.
Keywords: stress hormones; glucocorticoid responsive; air; ozone ... See more keywords
Transcriptional glucocorticoid effects in the brain: Finding the relevant target genes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.13213
Abstract: Glucocorticoids are powerful modulators of brain function. They act via mineralocorticoid and glucocorticoid receptors (MR and GR). These are best understood as transcription factors. Although many glucocorticoid effects depend on the modulation of gene transcription,… read more here.
Keywords: effects brain; target genes; brain; glucocorticoid effects ... See more keywords
Daidzein and its Effects on Brain.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867323666161101140214
Abstract: Among naturally occurring isoflavones, soy isoflavones are an important class with various biological activities. Due to their phytoestrogenic structure, their effects on the brain are profound thus making the neurobiological effects of these compounds an… read more here.
Keywords: daidzein effects; chemistry; daidzein; effects brain ... See more keywords
Short-term isolation effects on the brain, cognitive performance, and sleep—The role of exercise
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.903072
Abstract: Isolation is stressful and negatively affects sleep and mood and might also affect the structure and function of the brain. Physical exercise improves brain function. We investigated the influence of physical exercise during isolation on… read more here.
Keywords: effects brain; function; brain; isolation ... See more keywords
Cannabis: Neuropsychiatry and Its Effects on Brain and Behavior
Sign Up to like & getrecommendations! Published in 2020 at "Brain Sciences"
DOI: 10.3390/brainsci10110834
Abstract: Possibly orally transmitted from before circa 2000 B [...]. read more here.
Keywords: neuropsychiatry effects; brain behavior; cannabis neuropsychiatry; brain ... See more keywords