FOS‐Mediated PLCB1 Induces Radioresistance and Weakens the Antitumor Effects of CD8+ T Cells in Triple‐Negative Breast Cancer
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DOI: 10.1002/mc.23834
Abstract: Radioresistance and immune evasion are interactive and crucial events leading to treatment failure and progression of human malignancies. This research studies the role of phospholipase C beta 1 (PLCB1) in these events in triple‐negative breast… read more here.
Keywords: cd8 cells; fos; antitumor effects; effects cd8 ... See more keywords
Cyr61 Alleviates Cholangitis by Inhibiting Cytotoxic Effects of CD8+ T Cells on Biliary Epithelial Cells
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DOI: 10.1007/s11596-021-2458-3
Abstract: Primary biliary cholangitis (PBC) is a chronic progressive cholestatic liver disease. In recent years, researchers have found that cysteine-rich angiogenic inducer 61 (Cyr61, also known as CCN1) has a potential role in reducing portal inflammation… read more here.
Keywords: epithelial cells; cytotoxic effects; pbc; cd8 cells ... See more keywords