Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.06.056
Abstract: Fluorescent 4-ethylthio-1,8-naphthalimides containing rhodium(I) N-heterocyclic carbene (NHC) and ruthenium (II) NHC fragments were synthesised and evaluated for their antiproliferative effects, cellular uptake and DNA-binding activity. Both types of organometallics triggered ligand dependent efficient cytotoxic effects… read more here.
Keywords: effects cellular; dna; fluorescent; antiproliferative effects ... See more keywords
Effects of Cellular Senescence on Dental Follicle Cells
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology"
DOI: 10.1159/000510014
Abstract: The dental follicle is part of the tooth germ, and isolated stem cells from this tissue (dental follicle cells; DFCs) are considered, for example, for regenerative medicine and immunotherapies. However somatic stem cells can also… read more here.
Keywords: effects cellular; dental follicle; follicle cells; senescence ... See more keywords
Beneficial effects of cellular coinfection resolve inefficiency in influenza A virus transcription
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010865
Abstract: For diverse viruses, cellular infection with single vs. multiple virions can yield distinct biological outcomes. We previously found that influenza A/guinea fowl/Hong Kong/WF10/99 (H9N2) virus (GFHK99) displays a particularly high reliance on multiple infection in… read more here.
Keywords: multiple infection; effects cellular; transcription; infection ... See more keywords
Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2020.00124
Abstract: The behavior of an animal has substantial effects on its metabolism. Such effects, including changes in the lipid composition of different organs, or changes in the turnover of the proteins, have typically been observed using… read more here.
Keywords: effects cellular; spectrometry methods; metabolic effects; mass spectrometry ... See more keywords