Effects of CFTR modulators on pharmacokinetics of tobramycin during acute pulmonary exacerbations in the pediatric cystic fibrosis population
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DOI: 10.1002/ppul.24917
Abstract: Individuals with cystic fibrosis (CF) require higher dosages of aminoglycosides due to an increased volume of distribution (Vd) and clearance. Optimal dosing of aminoglycosides in the CF population is essential as repeated exposure to aminoglycosides… read more here.
Keywords: cystic fibrosis; effects cftr; fibrosis; pulmonary exacerbations ... See more keywords