Divergent effects of cholesterol on the structure and fluidity of liposome and catanionic vesicle membranes
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14375
Abstract: Lipid‐like ion‐pair amphiphile vesicles, or catanionic vesicles, have emerged as potential drug carriers. The effects of cholesterol on the properties of catanionic vesicles have yet been systematically studied. Here, we compared the effects of cholesterol… read more here.
Keywords: divergent effects; effects cholesterol; structure fluidity; catanionic vesicles ... See more keywords
Effects of Cholesterol on GPCR Function: Insights from Computational and Experimental Studies.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-14265-0_5
Abstract: The extensive experimental and computational evidences revealed that cholesterol is involved in the drug binding to G protein-coupled receptor (GPCR) targets that is influenced by the membrane environment and external functions. These multifunctional factors make… read more here.
Keywords: cholesterol gpcr; function insights; insights computational; gpcr function ... See more keywords
Concentration-Dependent Effects of Cholesterol on the Dimerization of Amyloid-β Peptides in Lipid Bilayers.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00349
Abstract: Membrane disruption mediated by the accumulation of amyloid-β (Aβ) on cell membranes is central to the pathogenesis of Alzheimer's disease (AD). Cholesterol, an important component of membranes, is well-recognized as a risk factor in AD.… read more here.
Keywords: amyloid; effects cholesterol; dimerization; membrane ... See more keywords
Effects of cholesterol on the anionic magnetite nanoparticle-induced deformation and poration of giant lipid vesicles
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DOI: 10.1039/d2ra03199j
Abstract: We have investigated the effects of cholesterol on the deformation and poration of giant unilamellar vesicles (GUVs) induced by anionic magnetite nanoparticles (NPs). Negatively charged lipid, neutral lipid, and cholesterol were used to prepare the… read more here.
Keywords: deformation; effects cholesterol; deformation poration; cholesterol ... See more keywords
Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review
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DOI: 10.3390/nu11112588
Abstract: Atherosclerosis, the main contributor to coronary heart disease, is characterised by an accumulation of lipids such as cholesterol in the arterial wall. Reverse cholesterol transport (RCT) reduces cholesterol via its conversion into bile acids (BAs).… read more here.
Keywords: cholesterol metabolism; cyp7a1; cholesterol; gut microbiota ... See more keywords