Abstract 1017: Vinorelbine, cyclophosphamide, and 5-FU effects on the circulating and intratumoral landscape of immune cells improve anti-PD-L1 efficacy in preclinical models of breast cancer and lymphoma
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DOI: 10.1158/1538-7445.am2018-1017
Abstract: Checkpoint inhibitors (CIs) are active in many types of cancer. However, only a minority of patients achieve complete and/or long-lasting responses. We studied the effects of 4 different doses of 3 widely-used, orally-active chemotherapeutics (vinorelbine,… read more here.
Keywords: vinorelbine cyclophosphamide; landscape; effects circulating; models breast ... See more keywords
Causal Effects of Circulating Lipid Traits on Epithelial Ovarian Cancer: A Two-Sample Mendelian Randomization Study
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DOI: 10.3390/metabo12121175
Abstract: Ovarian cancer (OC), and particularly epithelial OC (EOC), is an increasing challenge for women. Circulating lipids play different roles in the occurrence and development of OC, but no causal relationship has been confirmed. We used… read more here.
Keywords: two sample; sample mendelian; mendelian randomization; ovarian cancer ... See more keywords