PI3K Inhibition by BKM120 Results in Antiproliferative Effects on Corticotroph Tumor Cells
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DOI: 10.1210/jendso/bvab048.1116
Abstract: Abstract Purpose: Cushing’s disease is associated with significant morbidity, thus additional tumor-directed drugs with the potential to exert antineoplastic effects on corticotroph adenoma cells are desired. The PI3K (phosphoinositide-3-kinase)/AKT (protein kinase B) pathway, which plays… read more here.
Keywords: tumor; tumor cells; inhibition; corticotroph tumor ... See more keywords