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Published in 2021 at "Psychopharmacology"
DOI: 10.1007/s00213-021-05899-4
Abstract: Alzheimer's disease (AD) is a most common neurodegenerative disorder worldwide. Because of its complex pathogenesis, the prevention and therapies of AD still are a severe challenge. Evidence suggested that crocin, the major component of saffron,…
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Keywords:
crocin endogenous;
n2a app695swe;
induced neurotoxicity;
app695swe cells ... See more keywords
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Published in 2022 at "Neurochemical Research"
DOI: 10.1007/s11064-021-03501-z
Abstract: Several experimental and clinical findings suggest that ethanol consumption during pregnancy activates an oxidative-inflammatory cascade followed by wide apoptotic neurodegeneration within several brain areas, including the hippocampus. Crocin can protect neurons because of its antioxidant,…
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Keywords:
days birth;
neuroprotective effects;
effects crocin;
ethanol neurotoxicity ... See more keywords
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Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-10578-6
Abstract: The present study aimed to analyze the impact of tartrazine (T) and crocin (Cr) applications on the pancreas tissues of the Wistar rats. A total of 40 Wistar rats were randomly divided into 4 groups…
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Keywords:
administration;
ameliorative effects;
group;
study ... See more keywords
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Published in 2021 at "Andrologia"
DOI: 10.1111/and.14176
Abstract: Exposure to acrylamide (Ac) through food is almost inevitable and this kind of toxicity may cause lifelong harm. In present study, we researched effects of Crocin (Cr) on testis histopathology in Ac‐induced testis of rats.…
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Keywords:
induced testis;
crocin acrylamide;
acrylamide induced;
group ... See more keywords
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Published in 2022 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0468
Abstract: Abstract Paraquat (PQ) is a nonselective herbicide that induces oxidative reactions and multiple-organ failure on exposure. Crocin, a carotenoid obtained from saffron, has demonstrated many therapeutic effects against neural conditions because of its antioxidant properties.…
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Keywords:
crocin loaded;
brain;
crocin crocin;
crocin ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.830331
Abstract: Crocin, the main biologically active carotenoid of saffron, generally is derived from the dried trifid stigma of Crocus sativus L. Many studies have demonstrated that crocin has several therapeutic effects on biological systems through its…
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Keywords:
cartilage diseases;
cartilage;
bone cartilage;
crocin bone ... See more keywords