Articles with "effects dexmedetomidine" as a keyword



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Effects of dexmedetomidine alone or in combination with opioids on intraocular pressure in healthy Beagle dogs.

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Published in 2021 at "Veterinary anaesthesia and analgesia"

DOI: 10.1016/j.vaa.2021.04.001

Abstract: OBJECTIVE To evaluate the effects of dexmedetomidine alone or in combination with different opioids on intraocular pressure (IOP) in dogs. STUDY DESIGN Experimental, prospective, crossover, randomized, blinded study. ANIMALS A total of six Beagle dogs… read more here.

Keywords: combination; intraocular pressure; alone combination; dexmedetomidine alone ... See more keywords
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Effects of dexmedetomidine on new oxidative stress markers on renal ischaemia-reperfusion injury in rats: thiol/disulphide homeostasis and the ischaemia-modified albumin.

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Published in 2020 at "Archives of physiology and biochemistry"

DOI: 10.1080/13813455.2020.1754431

Abstract: Objectives: This study investigated the effect of dexmedetomidine on the oxidant-antioxidant (thiol/disulphide) balance.Methods: A total of 24 rats were divided into four groups. The renal arteries in groups IR (ischaemia/reperfusion) and IR + D (ischaemia/reperfusion + dexmedetomidine) were clamped… read more here.

Keywords: group; ischaemia; ischaemia reperfusion; effects dexmedetomidine ... See more keywords
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Cardiovascular effects of dexmedetomidine, with or without MK-467, following intravenous administration in cats.

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Published in 2017 at "Veterinary anaesthesia and analgesia"

DOI: 10.1111/vaa.12397

Abstract: OBJECTIVE To characterize the cardiovascular effects of dexmedetomidine, with or without MK-467, following intravenous (IV) administration in cats. STUDY DESIGN Prospective Latin square experimental study. ANIMALS Six healthy adult purpose-bred cats. METHODS Cats were anesthetized… read more here.

Keywords: administration; dexmedetomidine without; without 467; cardiovascular effects ... See more keywords
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The Effects of Dexmedetomidine on Microelectrode Recordings of the Subthalamic Nucleus during Deep Brain Stimulation Surgery: A Retrospective Analysis

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Published in 2017 at "Stereotactic and Functional Neurosurgery"

DOI: 10.1159/000453326

Abstract: Background: The placement of subthalamic nucleus (STN) deep brain stimulation (DBS) electrodes can be facilitated by intraoperative microelectrode recording (MER) of the STN. Objectives: Optimal anesthetic management during surgery remains unclear because of a lack… read more here.

Keywords: effects dexmedetomidine; dex; deep brain; stn ... See more keywords
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Ophthalmic effects of dexmedetomidine, methadone and dexmedetomidine–methadone in healthy cats and their reversal with atipamezole

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Published in 2022 at "Journal of Feline Medicine and Surgery"

DOI: 10.1177/1098612x221077023

Abstract: Objectives The aims of this study were to evaluate and compare the effects that dexmedetomidine and methadone, either alone or in combination, have on the ocular variables of healthy adult cats when administered intramuscularly, as… read more here.

Keywords: effects dexmedetomidine; dexmedetomidine methadone; methadone; healthy cats ... See more keywords
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Effects of dexmedetomidine pretreatment on rats with sepsis-induced acute kidney injury and miR-146a expression.

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Published in 2020 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2020.66.2.15

Abstract: The current research aimed to study the effects of dexmedetomidine (DEX) pretreatment on rats with sepsis-induced acute kidney injury (SAKI) and miR-146a expression. The model of SAKI was established through the tail vein injection of… read more here.

Keywords: mir 146a; expression; injury; effects dexmedetomidine ... See more keywords
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Effects of dexmedetomidine on glucose-related hormones and lactate in non-diabetic patients under general anesthesia: a randomized controlled trial.

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Published in 2021 at "Minerva anestesiologica"

DOI: 10.23736/s0375-9393.21.15734-7

Abstract: BACKGROUND To explore the effects of dexmedetomidine on glucose-related hormones and lactate levels in non-diabetic patients undergoing malignant gastrointestinal tumor radical resection. METHODS Groups D1 and D2 received dexmedetomidine loading dose 1 μg/kg and maintenance… read more here.

Keywords: diabetic patients; glucose related; dexmedetomidine glucose; non diabetic ... See more keywords
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Effects of dexmedetomidine and its reversal with atipamezole on echocardiographic measurements and circulating cardiac biomarker concentrations in normal cats.

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Published in 2022 at "Journal of the American Veterinary Medical Association"

DOI: 10.2460/javma.21.06.0299

Abstract: OBJECTIVE To investigate the effects of dexmedetomidine (DXM) and its subsequent reversal with atipamezole (APM) on the echocardiogram and circulating concentrations of cardiac biomarkers in cats. ANIMALS 14 healthy cats. PROCEDURES Cats underwent echocardiography and… read more here.

Keywords: effects dexmedetomidine; probnp concentrations; measurements circulating; pre ... See more keywords
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Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage.

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Published in 2023 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202301_31069

Abstract: OBJECTIVE Approximately 70% of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of cancer, radiotherapy can also affect and damage surrounding healthy tissues in addition to tumorous tissues. Since testicular tissues are… read more here.

Keywords: radioprotective effects; effects dexmedetomidine; damage; dexmedetomidine ray ... See more keywords
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Effects of Dexmedetomidine on Immune Cells: A Narrative Review

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.829951

Abstract: As we all know, dexmedetomidine (DEX), as a highly selective α2 adrenergic receptor agonist, exerts sedative, anti-anxiety and hypnotic effects by inhibiting the discharge of norepinephrine neurons in locus coeruleus and GABA-related hypnotic pathways. However,… read more here.

Keywords: effects dexmedetomidine; effects dex; cells narrative; dexmedetomidine immune ... See more keywords
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Effects of Dexmedetomidine on Immunomodulation and Pain Control in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial

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Published in 2023 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm13040622

Abstract: Aim: Digital and robotic technology applications in laparoscopic surgery have revolutionized routine cholecystectomy. Insufflation of the peritoneal space is vital for its safety but comes at the cost of ischemia-reperfusion-induced intraabdominal organ compromise before the… read more here.

Keywords: effects dexmedetomidine; group patients; control; placebo ... See more keywords