WWP2 overexpression inhibits the antitumor effects of doxorubicin in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11856
Abstract: Hepatocellular carcinoma (HCC) is a common liver cancer that accounts for 90% of cases. Doxorubicin exhibits a broad spectrum of antitumor activity and is one of the most active agents in HCC. WW domain‐containing protein… read more here.
Keywords: wwp2 overexpression; hepatocellular carcinoma; effects doxorubicin; wwp2 ... See more keywords
Effects of doxorubicin and apigenin on chronic myeloid leukemia cells (K562) in vitro: anti-proliferative and apoptosis induction assessments.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2069765
Abstract: In this study, we aimed to investigate the effect of the co-treatment with apigenin and doxorubicin (DOX) on K562 cells. Our results show that apigenin (0, 40, 60, 80 ,100 µM) and DOX (0-10 µM) as single… read more here.
Keywords: apoptosis; dox; effects doxorubicin; apigenin chronic ... See more keywords
Empaglifozin has cardioprotective and anti-inflammatory effects during doxorubicin treatment: A preclinical study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e23057
Abstract: e23057 Background: Empagliflozin (EMPA), a selective inhibitor of the sodium glucose co-transporter 2 (SGLT2), reduces the risk of hospitalization for heart failure or cardiovascular death in type 2 diabetic patients. We aimed to study if… read more here.
Keywords: cardioprotective anti; effects doxorubicin; doxo; inflammatory effects ... See more keywords
Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects
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DOI: 10.3389/fphar.2020.00567
Abstract: The success of cancer therapy is often compromised by the narrow therapeutic index of many anticancer drugs and the occurrence of drug resistance. The association of anticancer therapies with natural compounds is an emerging strategy… read more here.
Keywords: sulforaphane potentiates; cisplatin mitigates; doxorubicin cisplatin; potentiates anticancer ... See more keywords
The beneficial role of exercise in preventing doxorubicin-induced cardiotoxicity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1133423
Abstract: Doxorubicin is a highly effective chemotherapeutic agent widely used to treat a variety of cancers. However, the clinical application of doxorubicin is limited due to its adverse effects on several tissues. One of the most… read more here.
Keywords: induced cardiotoxicity; doxorubicin; cardiotoxicity; effects doxorubicin ... See more keywords
The Effects of Doxorubicin-based Chemotherapy and Omega-3 Supplementation on Mouse Brain Lipids
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DOI: 10.3390/metabo9100208
Abstract: Chemotherapy-induced cognitive impairment affects ~30% of breast cancer survivors, but the effects on how chemotherapy impacts brain lipids, and how omega-3 polyunsaturated fatty acid supplementation may confer protection, is unknown. Ovariectomized mice were randomized to… read more here.
Keywords: chemotherapy; supplementation; brain lipids; doxorubicin based ... See more keywords