Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloidâpredominant mouse model of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13165
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder with no cure. Limited treatment options available today do not offer solutions to slow or stop any of the suspected causes. The current medications used for the symptomatic… read more here.
Keywords: alzheimer disease; effects drug; disease; drug combination ... See more keywords
MGAE-DC: Predicting the synergistic effects of drug combinations through multi-channel graph autoencoders
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1010951
Abstract: Accurate prediction of synergistic effects of drug combinations can reduce the experimental costs for drug development and facilitate the discovery of novel efficacious combination therapies for clinical studies. The drug combinations with high synergy scores… read more here.
Keywords: multi channel; channel graph; synergistic effects; drug combinations ... See more keywords
Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug targets"
DOI: 10.2174/1389450118666170607104251
Abstract: OBJECTIVE This review article focuses on the neuroprotective effect of drug-induced hypothermia in cerebrovascular diseases and discusses its related side effects. METHOD A systematic literature search was performed using Pubmed and Embase electronic databases for… read more here.
Keywords: neuroprotective effects; effects drug; drug induced; drug ... See more keywords