Early effects of empagliflozin on exercise tolerance in patients with heart failure: A pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cardiology"
DOI: 10.1002/clc.22899
Abstract: Sodium‐glucose linked transporter 2 inhibition recently emerged as a promising therapy for reducing the risk of heart failure (HF) in patients with type 2 diabetes mellitus (T2DM). However, there is a lack of data endorsing… read more here.
Keywords: exercise; effects empagliflozin; early effects; heart failure ... See more keywords
Effects of empagliflozin on erythropoiesis in heart failure: data from the Empire HF trial
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2735
Abstract: It remains unknown whether the consistently observed increase in haematocrit with sodium–glucose cotransporter 2 inhibitors is caused by diuresis‐associated haemoconcentration or increased erythropoiesis. We aimed to investigate the early effect of empagliflozin on erythropoiesis and… read more here.
Keywords: heart failure; erythropoiesis heart; empagliflozin erythropoiesis; effects empagliflozin ... See more keywords
Effects of Empagliflozin Treatment on Glycerol‐Derived Hepatic Gluconeogenesis in Adults with Obesity: A Randomized Clinical Trial
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DOI: 10.1002/oby.22854
Abstract: The aim of this study was to determine the effects of empagliflozin on glycerol‐derived hepatic gluconeogenesis in adults with obesity without type 2 diabetes mellitus (T2DM) using oral carbon 13 (13C)‐labeled glycerol. read more here.
Keywords: glycerol derived; derived hepatic; glycerol; hepatic gluconeogenesis ... See more keywords
Effects of empagliflozin on markers of liver steatosis and fibrosis and their relationship to cardiorenal outcomes
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DOI: 10.1111/dom.14670
Abstract: Empagliflozin treatment reduced liver fat in small type 2 diabetes cohorts. This post‐hoc study evaluated effects of empagliflozin on risk for non‐alcoholic fatty liver disease‐related steatosis and fibrosis, as well as the relationship between risk… read more here.
Keywords: empagliflozin markers; relationship; cardiorenal outcomes; steatosis fibrosis ... See more keywords
Separate and combined effects of empagliflozin and semaglutide on vascular function: A 32‐week randomized trial
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DOI: 10.1111/dom.15464
Abstract: Despite the increasing use of combination treatment with sodium‐glucose cotransporter 2 inhibitors and glucagon‐like peptide‐1 receptor agonists, data are limited on the effects of combination treatment on markers of cardiovascular disease. This study aimed to… read more here.
Keywords: combined effects; effects empagliflozin; separate combined; vascular function ... See more keywords
Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction
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DOI: 10.1161/circulationaha.122.059755
Abstract: Background: Women and men with heart failure (HF) and preserved ejection fraction may differ in their clinical characteristics and their response to therapy. The aim of this study was to evaluate the influence of sex… read more here.
Keywords: preserved ejection; ejection fraction; effects empagliflozin; fraction ... See more keywords
Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092066
Abstract: Gliflozins (inhibitors of sodium-glucose cotransporter 2) show many beneficial actions beyond their antidiabetic effects. The underlying mechanisms of these additional protective effects are still not well understood, especially under non-diabetic conditions. Therefore, we analyzed the… read more here.
Keywords: inflammation; oxidative stress; effects empagliflozin; spontaneously hypertensive ... See more keywords
Effects of empagliflozin on cyclophosphamide-induced neurotoxicity in rats without diabetes
Sign Up to like & getrecommendations! Published in 2024 at "Turkish Journal of Medical Sciences"
DOI: 10.55730/1300-0144.5943
Abstract: Background/aim The objective of this study was to evaluate the effects of empagliflozin on cyclophosphamide-induced neurotoxicity in rats. Materials and methods A total of 32 male Wistar rats were separated into 4 groups with 8… read more here.
Keywords: cyclophosphamide induced; empagliflozin cyclophosphamide; group; effects empagliflozin ... See more keywords