The effects of genetic profiling on eating behaviour
Sign Up to like & getrecommendations! Published in 2017 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665117002841
Abstract: Abstract presented at Summer Meeting, 10–12 July 2017, Improving Nutrition in Metropolitan Areas. read more here.
Keywords: genetic profiling; profiling eating; eating behaviour; effects genetic ... See more keywords
Livestock Effects on Genetic Variation of Creosote Bushes in Patagonian Rangelands
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Conservation"
DOI: 10.1017/s0376892918000280
Abstract: Summary Genetic diversity is the raw material for species’ persistence over time, providing the potential to survive stochastic events, as well as climate and/or human-induced environmental changes. Biodiversity in dry rangelands is decreasing due to… read more here.
Keywords: genetic variation; livestock effects; creosote; effects genetic ... See more keywords
Effects of genetic polymorphism of drug-metabolizing enzymes on the plasma concentrations of antiepileptic drugs in Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2036916
Abstract: ABSTRACT As a chronic brain disease, epilepsy affects ~50 million people worldwide. The traditional antiepileptic drugs (AEDs) are widely applied but showing various problems. Although the new AEDs have partially solved the problems of traditional… read more here.
Keywords: plasma concentrations; drug metabolizing; enzymes plasma; drug ... See more keywords
A semi-supervised model to predict regulatory effects of genetic variants at single nucleotide resolution using massively parallel reporter assays.
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab040
Abstract: MOTIVATION Predicting regulatory effects of genetic variants is a challenging but important problem in functional genomics. Given the relatively low sensitivity of functional assays, and the pervasiveness of class imbalance in functional genomic data, popular… read more here.
Keywords: regulatory effects; semi supervised; genetic variants; effects genetic ... See more keywords
How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007075
Abstract: For a given gene, different mutations influence organismal phenotypes to varying degrees. However, the expressivity of these variants not only depends on the DNA lesion associated with the mutation, but also on factors including the… read more here.
Keywords: expressivity; ordering allelic; genetic background; effects genetic ... See more keywords
Effects of genetic information on memory for severity of depressive symptoms
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DOI: 10.1371/journal.pone.0239714
Abstract: The general public is increasingly aware of the role of genes in causing depression. Recent studies have begun uncovering unintended negative consequences of learning about a person’s genetic susceptibility to disorders. Because people tend to… read more here.
Keywords: depressive symptoms; depression; effects genetic; genetic information ... See more keywords
Effects of the genetic variants of organic cation transporters 1 and 3 on the pharmacokinetics of metformin in Jordanians
Sign Up to like & getrecommendations! Published in 2017 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2017-0019
Abstract: Abstract Background: Human response to the antidiabetic metformin is influenced by some factors, such as genetic variants in the SLC22A genes. This study aimed to determine the frequency of main SLC22A1 and SLC22A3 genetic variants… read more here.
Keywords: genetic variants; metformin; effects genetic; study ... See more keywords
Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.57345
Abstract: One life-threatening outcome of cardiovascular disease is myocardial infarction, where cardiomyocytes are deprived of oxygen. To study inter-individual differences in response to hypoxia, we established an in vitro model of induced pluripotent stem cell-derived cardiomyocytes… read more here.
Keywords: expression; dynamic effects; effects genetic; gene ... See more keywords