Molecular modeling of the effects of glycosylation on the structure and dynamics of human interferon-gamma
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DOI: 10.1007/s00894-019-4013-8
Abstract: Natural hIFNγ is a glycoprotein with two N-glycosylation sites in each monomer chain, which are independently and differentially glycosylated. Although glycosylation is not necessary for the activity of the cytokine, it was proposed that it… read more here.
Keywords: molecular modeling; effects glycosylation; modeling effects; glycosylation ... See more keywords
Insights into the effects of glycosylation and the monosaccharide-binding activity of the plant lectin CrataBL
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DOI: 10.1007/s10719-017-9766-7
Abstract: CrataBL is a glycoprotein isolated from Crataeva tapia bark, containing two N-glycosylation sites. It has been identified to present lectin activity with some specificity for binding glucose over galactose. However, to date, no information on… read more here.
Keywords: effects glycosylation; monosaccharide binding; cratabl; lectin ... See more keywords
Combined effects of glycosylation precursors and lactate on the glycoprofile of IgG produced by CHO cells.
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DOI: 10.1016/j.jbiotec.2018.11.004
Abstract: The glycosylation profile of therapeutic monoclonal antibodies (mAbs) is a crucial quality parameter for industrial Immunoglobulin G (IgG) production. Several alternative carbon sources, which function as glycosylation precursors, have been reported to impact the glycosylation… read more here.
Keywords: combined effects; igg; effects glycosylation; cho cells ... See more keywords