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Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00887
Abstract: Post-translational modifications of histone proteins often mediate gene regulation by altering the global and local stability of the nucleosome, the basic gene-packing unit of eukaryotes. We employed semisynthetic approaches to introduce histone H2B ubiquitylations at…
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Keywords:
histone h2b;
transcription;
transcription elongation;
h2b ubiquitylations ... See more keywords