Effects of immune cells and cytokines on inflammation and immunosuppression in the tumor microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106939
Abstract: Chronic inflammation and immune responses are two core element that characterize the tumor microenvironment. A large number of immune/inflammatory cells (including tumor associated macrophages, neutrophils and myeloid derived suppressor cells) as well as cytokines (such… read more here.
Keywords: tumor cells; tumor microenvironment; effects immune; tumor ... See more keywords
Interleukin-34 Limits the Therapeutic Effects of Immune Checkpoint Blockade
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101584
Abstract: Summary Interleukin-34 (IL-34) is an alternative ligand to colony-stimulating factor-1 (CSF-1) for the CSF-1 receptor that acts as a key regulator of monocyte/macrophage lineage. In this study, we show that tumor-derived IL-34 mediates resistance to… read more here.
Keywords: checkpoint blockade; immune checkpoint; blockade; effects immune ... See more keywords
Effects and immune responses of probiotic treatment in ruminants.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2018.12.006
Abstract: Gut microbial colonization and establishment are vital to ruminant health and production. This review article focuses on current knowledge and methods used to understand and manipulate the gut microbial community in ruminant animals, with a… read more here.
Keywords: microbial community; treatment; immune responses; responses probiotic ... See more keywords
Endocrine adverse effects of immune checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "Internal Medicine Journal"
DOI: 10.1111/imj.14992
Abstract: Immune checkpoint inhibitors are increasingly being utilised as an effective therapy for a variety of cancers. However, they have the potential to cause serious autoimmune toxicities in multiple organ systems termed ‘immunotherapy‐related adverse events’. Endocrine… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; effects immune; endocrine adverse ... See more keywords
Effects of an immune challenge on the thermal preferences of adult and newborn Liolaemus lizards from Patagonia, Argentina.
Sign Up to like & getrecommendations! Published in 2023 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202320201923
Abstract: Body temperature has relevant effects on the immune response. Here, we characterized the thermal biology and health condition of the viviparous lizard Liolaemus kingii from Patagonia (Argentina), by studying field body temperatures, presence of injuries… read more here.
Keywords: effects immune; challenge thermal; immune response; patagonia argentina ... See more keywords
Adverse Effects of Immune-Checkpoint Inhibitors: A Comprehensive Imaging-Oriented Review
Sign Up to like & getrecommendations! Published in 2023 at "Current Oncology"
DOI: 10.3390/curroncol30050355
Abstract: Immune-checkpoint inhibitors (ICIs) are immunomodulatory monoclonal antibodies, which increase antitumor immunity of the host and facilitate T-cell-mediated actions against tumors. These medications have been used in recent years as a weapon against advanced stage malignancies,… read more here.
Keywords: inhibitors comprehensive; checkpoint inhibitors; immune checkpoint; effects immune ... See more keywords