Effects of inhibition of phosphodiesterase 3B in pancreatic islets on insulin secretion: a potential link with some stimulatory pathways
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Physiology and Biochemistry"
DOI: 10.1080/13813455.2019.1628071
Abstract: Abstract Objective Elevated intracellular cAMP concentrations potentiate insulin secretion from pancreatic β cells. Phosphodiesterase 3B (PDE3B) is highly expressed in these cells and plays a role in the regulation of insulin secretion. Materials and methods… read more here.
Keywords: secretion; inhibition phosphodiesterase; insulin secretion; effects inhibition ... See more keywords
Allopregnanolone Effects on Inhibition in Hippocampal Parvalbumin Interneurons
Sign Up to like & getrecommendations! Published in 2023 at "eNeuro"
DOI: 10.1523/eneuro.0392-22.2023
Abstract: Abstract Allopregnanolone (AlloP) is a neurosteroid that potentiates ionotropic GABAergic (GABAA) inhibition and is approved for treating postpartum depression in women. Although the antidepressant mechanism of AlloP is largely unknown, it could involve selective action… read more here.
Keywords: inhibition; allopregnanolone effects; effects inhibition; parvalbumin interneurons ... See more keywords