Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2016.11.013
Abstract: Highlights • IL-1β is a key proinflammatory cytokine involved in ischemic brain damage.• Administration of IL-1Ra improves the stroke outcome in young and co-morbid rats.• Acute IL-1Ra administration also promotes neurogenesis after experimental stroke. read more here.
Keywords: receptor antagonist; morbid; reparative effects; antagonist young ... See more keywords
Expression, Regulation, and Effects of Interleukin-17f in the Human Ocular Surface
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2017.1316411
Abstract: ABSTRACT Purpose: To evaluate the basal and possibly stimulated expression of interleukin (IL)-17 in the context of the ocular surface and potential downstream effects. Methods: Western blot and immunofluorescent staining were used to evaluate IL-17F… read more here.
Keywords: ocular surface; effects interleukin; expression; regulation effects ... See more keywords
Paradoxical gastrointestinal effects of interleukin-17 blockers
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-218719
Abstract: We read with great interest the review written by Fauny et al 1 which describes the relevance of interleukin-23/T-helper 17 (IL-23/Th17) pathway in inflammatory bowel disease (IBD). However, drugs targeting IL-17 have shown the opposite… read more here.
Keywords: gastrointestinal effects; paradoxical gastrointestinal; effects interleukin; interleukin blockers ... See more keywords
Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032311
Abstract: Trained immunity is the process of long-term functional reprogramming (a de facto innate immune memory) of innate immune cells such as monocytes and macrophages after an exposure to pathogens, vaccines, or their ligands. The induction… read more here.
Keywords: opposing effects; interleukin interleukin; effects interleukin; immunity ... See more keywords