The effects of lapatinib on CYP3A metabolism of midazolam in patients with advanced cancer
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DOI: 10.1007/s00280-017-3470-y
Abstract: PurposeThe potential inhibition of CYP3A4 by lapatinib was studied using midazolam as a probe substrate in patients with cancer.MethodsThis was a partially randomized, 4-period, 4-sequence, 4-treatment, cross-over study in 24 patients with advanced cancer. Single… read more here.
Keywords: patients advanced; midazolam; effects lapatinib; cancer ... See more keywords