Evaluation of the effects of G4 ligands on the interaction between G-quadruplexes and their binding proteins.
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DOI: 10.1039/d5cc02801a
Abstract: G-quadruplexes (G4s) regulate multiple biological processes by interacting with G4-binding proteins (G4BPs). We developed a sandwich ELISA system to evaluate G4 ligand effects on G4-G4BP binding. G4 ligands strongly affect G-quartet-protein interactions, demonstrating that high… read more here.
Keywords: ligands interaction; interaction quadruplexes; binding proteins; evaluation effects ... See more keywords