Effects of Mavacamten on Measures of Cardiopulmonary Exercise Testing Beyond Peak Oxygen Consumption
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2022.5099
Abstract: This study examines the effect of mavacamten on exercise physiology using cardiopulmonary exercise testing. read more here.
Keywords: exercise testing; effects mavacamten; measures cardiopulmonary; cardiopulmonary exercise ... See more keywords
Effects of mavacamten on Ca2+ sensitivity of contraction as sarcomere length varied in human myocardium
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15271
Abstract: Heart failure can reflect impaired contractile function at the myofilament level. In healthy hearts, myofilaments become more sensitive to Ca2+ as cells are stretched. This represents a fundamental property of the myocardium that contributes to… read more here.
Keywords: ca2 sensitivity; myocardium; effects mavacamten; contraction ... See more keywords