Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4650-5
Abstract: Rationale3,4-Methylenedioxymethamphetamine (MDMA) is used recreationally and investigated as an adjunct to psychotherapy. Methylphenidate and modafinil are psychostimulants that are used to treat attention-deficit/hyperactivity disorder and narcolepsy, respectively, but they are also misused as cognitive enhancers.… read more here.
Keywords: effects mdma; methylphenidate modafinil; modafinil; endocrine ... See more keywords
Role of acute social stress in the rewarding effects of MDMA in adolescent mice
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113348
Abstract: Drug use among adolescents is a serious problem in our society, as some individuals develop dependence and addiction. MDMA/Esctasy is one of the most typically used substances by this age group. It is well known… read more here.
Keywords: social stress; effects mdma; rewarding effects; stress ... See more keywords
Role of serotonin transporter and receptor gene variations in the acute effects of MDMA in healthy subjects.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00590
Abstract: Methylenedioxymethamphetamine (MDMA; ecstasy) is used recreationally and has been investigated as an adjunct to psychotherapy. Most acute effects of MDMA can be attributed to activation of the serotonin (5-hydroxytryptamine [5-HT]) system. Genetic variants, such as… read more here.
Keywords: system; effects mdma; serotonin; acute effects ... See more keywords
Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants
Sign Up to like & getrecommendations! Published in 2024 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-024-01972-6
Abstract: Racemic 3,4-methylenedioxymethamphetamine (MDMA) acutely increases mood, feelings of empathy, trust, and closeness to others and is investigated to assist psychotherapy. Preclinical research indicates that S-MDMA releases monoamines and oxytocin more potently than R-MDMA, whereas R-MDMA… read more here.
Keywords: mdma; mdma 125; mdma administration; effects mdma ... See more keywords
Self-compassion mediates treatment effects in MDMA-assisted therapy for posttraumatic stress disorder
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Psychotraumatology"
DOI: 10.1080/20008066.2025.2485513
Abstract: ABSTRACT Background: Posttraumatic stress disorder (PTSD) is a severe condition often complicated by co-occurring disorders, such as major depression, alcohol use disorder, and substance use disorders. A well-powered phase 3 randomized, placebo-controlled trial has shown… read more here.
Keywords: therapy; posttraumatic stress; compassion; effects mdma ... See more keywords
Effects of MDMA on neuroplasticity, amyloid burden and phospho-tau expression in APPswe/PS1dE9 mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881119855987
Abstract: Background: 3,4-Methylenedioxymethamphetamine (MDMA) is still one of the most consumed drugs by adolescents. Its abuse is related with cognitive impairment, which seems due to maladaptive plasticity and neural stress. In turn, new hypotheses suggest that… read more here.
Keywords: effects mdma; expression; mice; mdma neuroplasticity ... See more keywords