The effects of melatonin on the concentrations of inflammatory cytokines and proteins, serotonin, cortisol and melatonin in ovariohysterectomised female dogs
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.1112
Abstract: Abstract Background Ovariohysterectomy (OHE) induces inflammation and stress in female dogs. The anti‐inflammatory effects of melatonin have been reported in several studies. Objectives The goal of this study was to assess the effects of melatonin… read more here.
Keywords: female dogs; effects melatonin; ohe; group ... See more keywords
Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-73234-9_31
Abstract: MicroRNAs (miRNAs) are endogenous short noncoding RNAs with approximately 22 nucleotides. The primary function of miRNAs is the negative regulation of target gene expression via mRNA degradation or translation inhibition. During recent years, much attention… read more here.
Keywords: effects melatonin; antitumor protective; roles micrornas; potential roles ... See more keywords
Pharmacological Effects of Melatonin as Neuroprotectant in Rodent Model: A Review on the Current Biological Evidence
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-019-00724-1
Abstract: The progressive loss of structure and functions of neurons, including neuronal death, is one of the main factors leading to poor quality of life. Promotion of functional recovery of neuron after injury is a great… read more here.
Keywords: effects melatonin; pharmacological effects; neuroprotectant rodent; injury ... See more keywords
Short- and Long-Term Protective Effects of Melatonin in a Mouse Model of Sepsis-Associated Encephalopathy
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0708-0
Abstract: Brain dysfunction is a common complication after sepsis and is an independent risk factor for a poor prognosis, which is partly attributed to the dysregulated inflammatory response and oxidative damage. Melatonin regulates the sleep–wake cycle… read more here.
Keywords: sepsis; treatment; dysfunction; sepsis associated ... See more keywords
Effects of melatonin feed on the changes of hemolymph immune parameters, antioxidant capacity, and mitochondrial functions in Chinese mitten crab (Eriocheir sinensis) caused by acute hypoxia
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736374
Abstract: Abstract Oxygen is essential for crustaceans, and hypoxia will have a negative impact on the growth and development of crustaceans. The aim of this study was to evaluate the protective effects of melatonin (MT) on… read more here.
Keywords: hemolymph immune; antioxidant capacity; immune parameters; effects melatonin ... See more keywords
The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2018.01.006
Abstract: OBJECTIVE Though the mechanisms are not clearly understood, melatonin and curcumin have been reported to have neuroprotective effects. However, the mechanisms of neuroprotective effects of melatonin and curcumin in the brain are not clearly understood.… read more here.
Keywords: hippocampus; sirt2 bcl; expression; melatonin curcumin ... See more keywords
Positive Effects of Melatonin on Renal Nitric Oxide-Asymmetric Dimethylarginine Metabolism in Fructose-Fed Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2020.0084
Abstract: Background: The incidence of metabolic syndrome is increasing worldwide and this is mainly attributed to high carbohydrate intake, especially of fructose, and sedentary lifestyles. Nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS)… read more here.
Keywords: group; adma; nitric oxide; asymmetric dimethylarginine ... See more keywords
Effects of melatonin on phosphorylation of memory-related proteins in the hippocampus and the perirhinal cortex in male mice
Sign Up to like & getrecommendations! Published in 2023 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001911
Abstract: We recently demonstrated that a single post-training administration of either melatonin, an MT1/MT2 melatonin receptor agonist ramelteon, or a brain melatonin metabolite N1-acetyl-5-methoxyquinuramine (AMK) enhanced object recognition memory. The present study aims to investigate the… read more here.
Keywords: effects melatonin; ramelteon amk; phosphorylation levels; memory ... See more keywords
Effects of melatonin supplementation on serum oxidative stress markers and disease activity in systemic lupus erythematosus patients: A randomised, double‐blind, placebo‐controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Practice"
DOI: 10.1111/ijcp.14246
Abstract: Considering pathological significance of oxidative stress in systemic lupus erythematosus (SLE), current research aimed to evaluate the effects of melatonin supplementation on oxidative stress markers and disease activity in SLE. read more here.
Keywords: systemic lupus; oxidative stress; lupus erythematosus; stress ... See more keywords
Leptin mediates the effects of melatonin on female reproduction in mammals
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12559
Abstract: Melatonin is a natural molecule produced in the pineal gland and other tissues. It participates in numerous biological activities including the regulation of reproduction. However, the mechanism by which melatonin affects mammalian female reproductive performance… read more here.
Keywords: reproduction; mediates effects; leptin; melatonin female ... See more keywords
Renal Protective Effects of Melatonin in Animal Models of Diabetes Mellitus-Related Kidney Damage: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Diabetes Research"
DOI: 10.1155/2022/3770417
Abstract: Diabetic nephropathy (DN)—chronic kidney damage caused by hyperglycemia—eventually develops into end-stage renal disease (ESRD). Melatonin is a powerful antioxidant that has a wide range of biological activities. Potentially helpful effects of melatonin on diabetic kidney… read more here.
Keywords: meta analysis; kidney damage; effects melatonin; group ... See more keywords